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Approach to Treatment of Patients with Vitiligo
Wright State University School of Medicine, Dayton, OH
And Group Health Associates of Cincinnati, Ohio
James J. Nordlund, MD
Updated 7 January 2007

GENERAL WORKUP

  • Patient history and complete skin examination
  • Discussion about pathogenesis and treatment
  • Ophthalmologic examination is optional and indicated only for those with signs or symptoms of chorioretinitis
  • Thyroid studies only for those with family history of thyroiditis or symptoms of thyroid disorder.
    (Refer to PCP for workup if preferred)
    Photographs (selected cases)
  • Make patients aware of National Vitiligo Foundation and local chapter

OPTIONS FOR TREATMENT

  • Sunscreen: Makeup:
    - DyoDerm Vitadye (stains)
    - Covermark, Dermablend
  • Repigmentation: Topical steroids used cautiously on face and intertriginous areas
  • Immunomodulators: tacrolimus or pimecrolimus used with topical steroids
  • Natural sunlight in sub erythemal doses
  • Narrow band ultraviolet light or excimer lasers
  • Tanning parlors with assistance of dermatologist
  • PUVA: Topical, Oral-8-MOP (Indoor only) is indicated only for the more complex cases where repigmentation is necessary and all other therapy has been unsuccessful.
  • Surgical therapies are available for carefully selected patients, especially those with focal or segmental vitiligo.
  • Depigmentation: - Monobenzylether of hydroquinone it should be assumed this is permanent and irreversible but some repigmentation can occur following sun exposure.) It takes several years to depigment the face, neck, hands and arms.

FOLLOW-UP OBJECTIVES

  • Access effectiveness of treatment
  • Explore old and new options (such as tattooing, micro grafting refractory macules)

Vitiligo treatment protocol

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